EGR-1-IN-1
CAT:
804-HY-163731-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
EGR-1-IN-1
- UNSPSC Description: EGR-1-IN-1 (IT25) is an inhibitor targeting EGR-1, with IC50 of 1.86 μM. EGR-1-IN-1 can be used in the research of inflammatory skin diseases[1].
- Target Antigen: DNA Methyltransferase
- Type: Reference compound
- Related Pathways: Epigenetics
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/egr-1-in-1.html
- Solubility: DMF : 1.25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: COC1=CC2=C(/C(C(N2)=O)=N/NC(NC3=CC=C(C=C3)C#N)=S)C=C1
- Molecular Weight: 351.38
- References & Citations: [1]Ahn S, et al. Design, synthesis, and biological evaluation of 2-(2-oxoindolin-3-ylidene)hydrazinecarbothioamides as a potential EGR-1 inhibitor for targeted therapy of atopic dermatitis. Bioorg Chem. 2024 Jul;148:107481.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported