TCO-NHS ester
CAT:
804-HY-141165-02
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TCO-NHS ester
- CAS Number: 1191901-33-3
- UNSPSC Description: TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tco-nhs-ester.html
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 52°C)
- Smiles: O=C(OC1CC/C=C/CCC1)ON2C(CCC2=O)=O
- Molecular Weight: 267.281
- References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported