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α,β-Methylene-ATP (trisodium)

CAT:
804-HY-108652-02
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
α,β-Methylene-ATP (trisodium) - image 1

α,β-Methylene-ATP (trisodium)

  • CAS Number: 1343364-54-4
  • UNSPSC Description: α,β-Methylene-ATP trisodium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand[1]. α,β-Methylene-ATP trisodium is a highly selective agonist for P2X1 and P2X3, with practically no activity at P2X2,4-7[2].
  • Target Antigen: P2X Receptor
  • Type: Reference compound
  • Related Pathways: Membrane Transporter/Ion Channel
  • Applications: COVID-19-immunoregulation
  • Field of Research: Inflammation/Immunology
  • Assay Protocol: https://www.medchemexpress.com/α-β-methylene-atp-trisodium.html
  • Purity: 99.75
  • Solubility: H2O : 125 mg/mL (ultrasonic)
  • Smiles: O=P(O)([O])OP(CP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O1)(O[Na])=O)(O[Na])=O.[Na]
  • Molecular Weight: 571.15
  • References & Citations: [1]Arribas-Blázquez M, et al. Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain. Int J Mol Sci. 2019 Jan 3;20(1).|[2]Claudio Coddou, et al. Activation and regulation of purinergic P2X receptor channels. Pharmacol Rev. 2011 Sep;63(3):641-83
  • Shipping Conditions: Blue Ice
  • Storage Conditions: -20°C (Powder, stored under nitrogen)
  • Clinical Information: No Development Reported