Uridine-5'-O-(3-thiotriphosphate)

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804-HY-137603

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CAS Number: 79049-97-1
UNSPSC Description: Uridine-5'-O-(3-thiotriphosphate) (UTPγS), a stable analogue of UTP, is a potent agonist of the P2Y2 and P2Y4 receptors with increased metabolic stability[1][2].
Target Antigen: P2Y Receptor
Type: Reference compound
Related Pathways: GPCR/G Protein
Applications: Metabolism-protein/nucleotide metabolism
Field of Research: Metabolic Disease
Assay Protocol: https://www.medchemexpress.com/uridine-5-o-3-thiotriphosphate.html
Smiles: O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1COP(OP(OP(O)(S)=O)(O)=O)(O)=O
Molecular Weight: 500.21
References & Citations: [1]Anna-Karin Wihlborg, et al. Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction. Circ Res. 2006 Apr 14;98(7):970-6.|[2]Malin Malmsjö, et al. The stable pyrimidines UDPβS and UTPγS discriminate between the P2 receptors that mediate vascular contraction and relaxation of the rat mesenteric artery. Br J Pharmacol. 2000 Sep;131(1):51-6.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-137603	Uridine-5'-O-(3-thiotriphosphate)
HY-108651	Uridine-5'-O-(3-thiotriphosphate) (trisodium)
HY-W590551	Adenosine 5′-O-(1-thiotriphosphate)
HY-W590551A	Adenosine 5′-O-(1-thiotriphosphate) (disodium)
HY-154217	3′,5′-Bis-O-(triphenylmethyl)uridine
HY-137608	Uridine 5'-O-thiodiphosphate
HY-134337	5'-O-DMTr-3'-O-methyl uridine-3'-CED-phosphoramidite
HY-154550	2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-5-methyl uridine
HY-154543	5’-O-(4,4’-Dimethoxytrityl)-3’-O-(2-methoxyethyl) uridine
HY-154640	2’,3’,5’-Tri-O-acetyl-5-(trifluoromethyl)uridine

Cat	Name
A9081-2.5	Uridine-5'-O-(3-thiotriphosphate) (sodium salt)
MBS256552-02	Uridine- 5'- O- (3- thiotriphosphate) (UTP-gamma-S)
MBS256552-01	Uridine- 5'- O- (3- thiotriphosphate) (UTP-gamma-S)
sc-202639	Guanosine 5'-O-(3-thiotriphosphate) tetralithium salt
MBS256323-02	Uridine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-UTP-alpha-S)
MBS256061-02	Uridine- 5'- O- (1- thiotriphosphate), Rp- isomer (Rp-UTP-alpha-S)
MBS256323-01	Uridine- 5'- O- (1- thiotriphosphate), Sp- isomer (Sp-UTP-alpha-S)
MBS256061-01	Uridine- 5'- O- (1- thiotriphosphate), Rp- isomer (Rp-UTP-alpha-S)
MBS256587-02	3'- Deoxythymidine- 5'- O- (1- thiotriphosphate) (dTTP-alpha-S) / 2', 3'- Dideoxythymidine- 5'- O- (1- thiotriphosphate) (ddTTP-alpha-S)
MBS256277-02	Guanosine- 5'- O- (3- thiotriphosphate) (GTP-gamma-S)