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N,N'-Dimethylthiourea

CAT:
804-HY-W027951-01
Size:
500 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
N,N'-Dimethylthiourea - image 1

N,N'-Dimethylthiourea

  • CAS Number: 534-13-4
  • UNSPSC Description: N,N'-Dimethylthiourea (DMTU), isolated from Allium sativum, is an orally active scavenger of hydroxyl radical (•OH) and blocks •OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including •OH scavenging and anti-inflammatory action[1][2].
  • Target Antigen: Reactive Oxygen Species
  • Type: Natural Products
  • Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
  • Applications: COVID-19-anti-virus
  • Field of Research: Inflammation/Immunology
  • Assay Protocol: https://www.medchemexpress.com/n-n-dimethylthiourea.html
  • Purity: 99.93
  • Solubility: DMSO : 100 mg/mL (ultrasonic)
  • Smiles: S=C(NC)NC
  • Molecular Weight: 104.17
  • References & Citations: [1]Yoshiji Ohta, et al. Protective effect of N,N'-dimethylthiourea against stress-induced gastric mucosal lesions in rats. Fundam Clin Pharmacol. 2017 Jun;31(3):319-328.|[2]Zhongyi Zhang, et al. Analysis of volatile compounds in fermented black garlic by GC-MS.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: RT, stored under nitrogen
  • Clinical Information: No Development Reported