(R)-(-)-Rolipram
CAT:
804-HY-16900A-03
Size:
10 mM / 1 mL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(R)-(-)-Rolipram
- CAS Number: 85416-75-7
- UNSPSC Description: (R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterases PDE4 with IC50 of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
- Target Antigen: Phosphodiesterase (PDE)
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/_R_-_-_-Rolipram.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C1NC[C@@H](C2=CC=C(OC)C(OC3CCCC3)=C2)C1
- Molecular Weight: 275.348
- References & Citations: [1]Guo C, et al. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. 2016 Oct 18;45(4):944.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported