4-(Azidomethyl)benzoic acid

4-(Azidomethyl)benzoic acid

• CAS Number: 79584-03-5
• UNSPSC Description: 4-(Azidomethyl)benzoic acid is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
• Target Antigen: ADC Linker
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/4-azidomethyl-benzoic-acid.html
• Solubility: 10 mM in DMSO
• Smiles: [N-]=[N+]=NCC1=CC=C(C(O)=O)C=C1
• Molecular Weight: 177.16
• References & Citations: [1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported