Berberine (chloride)
CAT:
804-HY-18258-01
Size:
5 g
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Berberine (chloride)
- CAS Number: 633-65-8
- UNSPSC Description: Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].
- Target Antigen: Antibiotic; Autophagy; Bacterial; Endogenous Metabolite; Parasite; Reactive Oxygen Species; Topoisomerase
- Type: Natural Products
- Related Pathways: Anti-infection;Autophagy;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Berberine-chloride.html
- Purity: 99.69
- Solubility: DMSO : 8.33 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)
- Smiles: COC1=C(OC)C2=C[N+]3=C(C(C(CC3)=C4)=CC5=C4OCO5)C=C2C=C1.[Cl-]
- Molecular Weight: 371.81
- References & Citations: [1]Cai Y, et al. Berberine inhibits the growth of human colorectal adenocarcinoma in vitro and in vivo. J Nat Med. 2014 Jan;68(1):53-62.Aquacult Nutr. 14 Jul 2022.|Biochem Pharmacol. 2021 Apr 27;114576.|Front Pharmacol. 2023 Apr 18:14:1148611.|Inflammopharmacology. 2024 May 17.|Int Immunopharmacol. 2024 May 29:136:112278.|Int Immunopharmacol. 2024 Sep 24;142(Pt B):113227.|J Appl Toxicol. 2024 Jul 9.|Mech Ageing Dev. 2020 Oct;191:111347.|Molecules. 2024 May 14.|Oncologie. 2023 Mar 10.|Phytomedicine. 2023 Jul 17, 154962.|Research Square Preprint. 2021 May.|Research Square Print. 2022 Aug.|Acta Pharmacol Sin. 2022 Aug 10.|Appl Biochem Biotechnol. 2023 Dec 28.|Aquaculture. 15 May 2022, 738055.|Biol Pharm Bull. 2022 Jul 20.|Biomed Pharmacother. 2023 Dec 18:170:116012.|BMC Pharmacol Toxicol. 2023 May 11;24(1):29.|Evid-Based Compl Alt. 2021 May 4.|Exp Cell Res. 2020 Aug 1;393(1):112054.|Exp Cell Res. 2024 May 13:114094.|Fish Shellfish Immunol. 2024 Mar 26:109522.|Food Chem Toxicol. 2023 Mar 25;113743.|Gene. 2022 Jan 10;146171.|Hepatol Commun. 2024 Mar 29;8(4):e0405.|Int J Nanomedicine. 2023 Jul 31.|J Bone Miner Metab. 2021 Apr 8.|J Ethnopharmacol. 2024 Apr 24:324:117829.|J Ethnopharmacol. 8 November 2021, 114786.|J Pharm Pharmacol. 2022 May 31;rgac026.|JCI Insight. 2023 Jul 24;8(14):e166306.|Mol Med Rep. 2023 Jan;27(1):17.|Pharm Biol. 2024 Dec;62(1):53-61.|Phytomedicine. 2023 Dec 2, 155247.|Research Square Preprint. 2021 Jun.|Research Square Preprint. 2021 Sep.|Sci Rep. 2022 Oct 17;12(1):17350.|SSRN. 2023 Jan 27.|Cardiovasc Drugs Ther. 2021 Jul 28.|J Appl Microbiol. 2021 Apr;130(4):1154-1172.|Microbiol Spectr. 2023 Sep 25;e0217023.|Int Immunopharmacol. 2024 Apr 18:133:112036.|Mol Reprod Dev. 2024 Aug;91(8):e23768.|Phytomedicine. 2024 Sep 30:135:156111.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched