14-Deoxy-11,12-didehydroandrographolide

14-Deoxy-11,12-didehydroandrographolide

• CAS Number: 42895-58-9
• UNSPSC Description: 14-Deoxy-11,12-didehydroandrographolide is an analogue of Andrographolide. 14-Deoxy-11,12-didehydroandrographolide inhibits NF-κB activation.
• Target Antigen: NF-κB
• Type: Natural Products
• Related Pathways: NF-κB
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Cancer
• Assay Protocol: https://www.medchemexpress.com/14-Deoxy-11,12-didehydroandrographolide.html
• Purity: 99.91
• Solubility: DMF : 100 mg/mL (ultrasonic)|DMSO : 110 mg/mL (ultrasonic)
• Smiles: O=C1OCC=C1/C=C/[C@@H]2C(CC[C@]3([H])[C@](C)(CO)[C@H](O)CC[C@@]23C)=C
• Molecular Weight: 332.43
• References & Citations: [1]Guan SP, et al. Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue ofandrographolide, in allergic airway inflammation. J Nat Prod. 2011 Jun 24;74(6):1484-90.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported