Carboxyatractyloside (tripotassium)

Carboxyatractyloside (tripotassium)

• CAS Number: 77228-71-8
• UNSPSC Description: Carboxyatractyloside (Gummiferin) tripotassium is a toxic natural product, acts as an inhibitor of ADP/ATP carrier, inhibits mitochondrial ADP/ATP transport from the inner mitochondria to the inner mitochondria. Carboxyatractyloside tripotassium can be used for the study of cellular energy metabolism and mitochondrial biology[1].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/carboxyatractyloside-tripotassium.html
• Purity: 99.74
• Solubility: H2O : ≥ 50 mg/mL
• Smiles: C=C([C@H](CC1)C2)[C@H](O)[C@@]32CC[C@]4([H])[C@@](C(O)=O)(C(O[K])=O)C[C@@H](O[C@@H]5[C@H]([C@@H]([C@H]([C@H](CO)O5)OS(=O)(O[K])=O)OS(=O)(O[K])=O)OC(CC(C)C)=O)C[C@@]4(C)[C@@]31[H]
• Molecular Weight: 885.09
• References & Citations: [1]Pebay-Peyroula E, et al. Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature. 2003 Nov 6;426(6962):39-44.EMBO Mol Med. 2021 Dec 7;13(12):e14072.|Redox Biol. 2024 May 23:73:103207.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported