N-Desmethyl imatinib (mesylate)

N-Desmethyl imatinib (mesylate)

• CAS Number: 404844-03-7
• UNSPSC Description: N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR[1].
• Target Antigen: Drug Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/n-desmethyl-imatinib-mesylate.html
• Solubility: 10 mM in DMSO
• Smiles: CS(=O)(O)=O.O=C(NC1=CC=C(C)C(NC2=NC(C3=CC=CN=C3)=CC=N2)=C1)C4=CC=C(CN5CCNCC5)C=C4
• Molecular Weight: 575.68
• References & Citations: [1]Robert A Parise, et al. Liquid chromatographic-mass spectrometric assay for quantitation of imatinib and its main metabolite (CGP 74588) in plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jul 5;791(1-2):39-44.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported