RI-2

RI-2

• CAS Number: 1417162-36-7
• UNSPSC Description: RI-2 is a reversible RAD51 inhibitor, with an IC50 of 44.17 μM, and specifically inhibits homologous recombination repair in human cells.
• Target Antigen: RAD51
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/RI-2.html
• Solubility: DMSO : 130 mg/mL (ultrasonic)
• Smiles: O=C(C(C1=CC=C(OC)C=C1)=C2N3CCOCC3)N(C4=CC=C(Cl)C(Cl)=C4)C2=O
• Molecular Weight: 433.28
• References & Citations: [1]Budke B, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56(1):254-63.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported