Alpha Actin Antibody / ACTA2 (smooth muscle)

Alpha Actin Antibody / ACTA2 (smooth muscle)

• Description: Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This mAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
• CAS Number: 9007-83-4
• UniProt: P62736
• Host: Mouse
• Immunogen: Recombinant full-length human protein was used as the immunogen for the Alpha Smooth Muscle Actin antibody.
• Clonality: Monoclonal
• Isotype: IgG2a κ
• Applications: IF, IHC-P
• Format: Purified
• Buffer: 1 mg/ml in 1X PBS; BSA free, sodium azide free
• Reconstitution: Store the Alpha Smooth Muscle Actin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This Alpha Smooth Muscle Actin antibody is available for research use only.