LY117018 (TFA)
CAT:
804-HY-116896A-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
LY117018 (TFA)
- CAS Number: 2390041-98-0
- UNSPSC Description: LY117018 TFA, a Raloxifene analog, is a selective estrogen receptor modulator. LY117018 TFA exerts antiproliferative effects on breast cancer cell lines[1][2][3].
- Target Antigen: Estrogen Receptor/ERR
- Type: Reference compound
- Related Pathways: Vitamin D Related/Nuclear Receptor
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ly117018-tfa.html
- Purity: 99.18
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: FC(F)(C(O)=O)F.O=C(C1=CC=C(C=C1)OCCN2CCCC2)C3=C(SC4=CC(O)=CC=C43)C5=CC=C(C=C5)O
- Molecular Weight: 573.58
- References & Citations: [1]Dinda S, et al. Effects of LY117018 (a SERM analog of raloxifene) on tumor suppressor proteins and proliferation of breast cancer cells.Horm Mol Biol Clin Investig. 2010 Aug 1;2(1):211-7.|[2]Baumann KH, et al. Effects of celecoxib and ly117018 combination on human breast cancer cells in vitro.Breast Cancer (Auckl). 2009 Apr 7;3:23-34.|[3]Yu J, et al.Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK1/2 signaling pathway.Eur J Pharmacol. 2008 Jul 28;589(1-3):32-6.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported