SOX2 Antibody (phospho-S246)

SOX2 Antibody (phospho-S246)

• Description: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
• CAS Number: 9007-83-4
• UniProt: P48431
• Host: Rabbit
• Immunogen: This phospho-SOX2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS246 of human SOX2.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: IF, DB, ELISA
• Format: Antigen affinity purified
• Buffer: In 1X PBS pH 7.4 with 0.09% sodium azide
• Reconstitution: Aliquot the phospho-SOX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This phospho-SOX2 antibody is available for research use only.