STAT3-IN-34
CAT:
804-HY-169007
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
STAT3-IN-34
- UNSPSC Description: STAT3-IN-34 (Compound 15E) is an inhibitor for STAT3, and inhibits the nuclear translocation and transcriptional regulator activity of STAT3. STAT3-IN-34 inhibits the proliferation of cell HaCaT with IC50 of 0.008 μM. STAT3-IN-34 inhibits IL-17A expression and ameliorates Imiquimod (HY-B0180)-induced psoriasis in mice[1].
- Target Antigen: STAT
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;Stem Cell/Wnt
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/stat3-in-34.html
- Smiles: CN(CCOC1=CC=C(C=C1)C2=NOC3=C2C(C4=C(C3=O)C=CS4)=O)C
- Molecular Weight: 368.41
- References & Citations: [1]Chen L, et al., Design, Synthesis, and Biological Activity of Novel Quinone Derivatives as Potent STAT3 Inhibitors for Psoriasis Treatment. J Med Chem. 2024 Aug 16.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported