Allocryptopine

CAT:

804-HY-N1933-01

Size:

5 mg

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CAS Number: 485-91-6
UNSPSC Description: Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Macleaya cordata (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current[1][2].
Target Antigen: Potassium Channel
Type: Natural Products
Related Pathways: Membrane Transporter/Ion Channel
Applications: Neuroscience-Neuromodulation
Field of Research: Cardiovascular Disease
Assay Protocol: https://www.medchemexpress.com/allocryptopine.html
Purity: 99.74
Solubility: DMSO : 50 mg/mL (ultrasonic)
Smiles: O=C1C(C(CCN(C)CC2=C(OC)C(OC)=CC=C2C1)=C3)=CC4=C3OCO4
Molecular Weight: 369.41
References & Citations: [1]Xu B, et al. Effect of α-Allocryptopine on Delayed Afterdepolarizations and Triggered Activities in Mice Cardiomyocytes Treated with Isoproterenol. Evid Based Complement Alternat Med. 2015;2015:634172.|[2]Lin K, et al. Allocryptopine and benzyltetrahydropalmatine block hERG potassium channels expressed in HEK293 cells. Acta Pharmacol Sin. 2013 Jun;34(6):847-58.
Shipping Conditions: Blue Ice
Storage Conditions: -20°C (Powder, protect from light)
Clinical Information: No Development Reported