Oxybutynin

Oxybutynin

• CAS Number: 5633-20-5
• UNSPSC Description: Oxybutynin is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1]. Oxybutynin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: mAChR; Potassium Channel
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/Oxybutynin.html
• Purity: 99.55
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 50 mg/mL
• Smiles: O=C(C(O)(C1=CC=CC=C1)C2CCCCC2)OCC#CCN(CC)CC
• Molecular Weight: 357.49
• References & Citations: [1]Li H, et al. The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036. |[2]Oki T, et al. Comparative evaluation of central muscarinic receptor binding activity by oxybutynin, tolterodine and darifenacin used to treat overactive bladder. J Urol. 2007 Feb;177(2):766-70.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched