Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan

Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan

• CAS Number: 1599439-54-9
• UNSPSC Description: Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a drug-linker conjugate for ADC. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan consists of Exatecan (HY-13631) and a linker. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan can be used for synthesis of ADCs and for cancer research[1].
• Target Antigen: Drug-Linker Conjugates for ADC; Topoisomerase
• Type: ADC Related
• Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mal-peg2-gly-gly-phe-gly-exatecan.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C=CC1=O)N1CCC(NCCOCCOCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCCCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 1149.18
• References & Citations: [1]Masuda Takeshi, et al. Preparation of antibody-drug conjugates for cancer therapy. Patent WO2014057687.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported