Mal-​PEG4-​propargyl

Mal-​PEG4-​propargyl

• CAS Number: 1262681-30-0
• UNSPSC Description: Mal-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Mal-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mal-peg4-propargyl.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C=C1)N(CCOCCOCCOCCOCC#C)C1=O
• Molecular Weight: 311.33
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported