1-Methyl-2-undecyl-4(1H)-quinolone

CAT:

804-HY-N1638-02

Size:

25 mg

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CAS Number: 59443-02-6
UNSPSC Description: 1-Methyl-2-undecyl-4(1H)-quinolone is a potent, irreversible and selective inhibitor of type B monoamine oxidase (MAO-B). 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of MAO-B activity with the IC50 and Ki values of 15.3 μM and 9.91 μM, respectively, but did not inhibit type A MAO (MAO-A) activity. Methyl-2-undecyl-4(1H)-quinolone, as a quinolone alkaloid, is isolated from fresh leaves and fruits of Evodia rutaecarpa HOOK. f. et THOMS[1][2].
Target Antigen: Monoamine Oxidase
Type: Natural Products
Related Pathways: Neuronal Signaling
Applications: Neuroscience-Neuromodulation
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/1-methyl-2-undecyl-4-1h-quinolone.html
Solubility: 10 mM in DMSO
Smiles: O=C1C=C(CCCCCCCCCCC)N(C)C2=C1C=CC=C2
Molecular Weight: 313.48
References & Citations: [1]Toshiya K, et al. Isolation and Structure Elucidation of Three Quinolone|[2]Lee MK, et al. 1-methyl-2-undecyl-4(1H)-quinolone as an irreversible and selective inhibitor of type B monoamine oxidase. Chem Pharm Bull (Tokyo). 2003;51(4):409-411.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-N1638-02	1-Methyl-2-undecyl-4(1H)-quinolone
HY-N1638-03	1-Methyl-2-undecyl-4(1H)-quinolone
HY-N1638-01	1-Methyl-2-undecyl-4(1H)-quinolone
HY-N1636	1-Methyl-2-nonyl-4(1H)-quinolone
HY-D0113	7-Hydroxy-4-methyl-2(1H)-quinolone
HY-N0968-02	1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone
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HY-N0968-03	1-Methyl-2-[(Z)-6-undecenyl]-4(1H)-quinolone
HY-N9520-01	1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
HY-N9520-02	1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone