Sphingomyelin

Sphingomyelin

• CAS Number: 85187-10-6
• UNSPSC Description: Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann–Pick disease[1][2][3][4].
• Target Antigen: Endogenous Metabolite
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease; Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/Sphingomyelin.html
• Purity: 99.0
• Solubility: Ethanol : 25 mg/mL (ultrasonic)
• Smiles: [Sphingomyelin]
• References & Citations: [1]Chakraborty M, et al. Sphingomyelin and its role in cellular signaling. Adv Exp Med Biol. 2013;991:1-14.|[2]Schneider N, et al. Sphingomyelin in Brain and Cognitive Development: Preliminary Data. eNeuro. 2019 Aug 6;6(4). pii: ENEURO.0421-18.2019.|[3]Bienias K, et al. Regulation of sphingomyelin metabolism. Pharmacol Rep. 2016 Jun;68(3):570-81.|[4]Schuchman EH, et al. Types A and B Niemann-Pick disease. Mol Genet Metab. 2017 Jan - Feb;120(1-2):27-33.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported