Tenofovir amibufenamide

Tenofovir amibufenamide

• CAS Number: 1571076-26-0
• UNSPSC Description: Tenofovir amibufenamide (HS-10234), a Tenofovir prodrug, is an orally active antiviral agent. Tenofovir amibufenamide inhibits HBV, and can be used for chronic hepatitis B (CHB) study[1][2].
• Target Antigen: HBV
• Type: Reference compound
• Related Pathways: Anti-infection
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/tenofovir-amibufenamide.html
• Smiles: C[C@@H](OC[P@](OC1=CC=CC=C1)(NC(C)(C)C(OC(C)C)=O)=O)CN2C3=NC=NC(N)=C3N=C2
• Molecular Weight: 490.49
• References & Citations: [1]Zhihong Liu, et al. Randomised clinical trial: 48 weeks of treatment with tenofovir amibufenamide versus tenofovir disoproxil fumarate for patients with chronic hepatitis B. Aliment Pharmacol Ther. 2021 Nov;54(9):1134-1149.|[2]Hong Zhang, et al. Randomised clinical trial: safety, efficacy and pharmacokinetics of HS-10234 versus tenofovir for the treatment of chronic hepatitis B infection. Aliment Pharmacol Ther. 2021 Jan;53(2):243-252.
• Shipping Conditions: Room Temperature