VEGFR-2/InhA-IN-1
CAT:
804-HY-159565
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

VEGFR-2/InhA-IN-1
- UNSPSC Description: VEGFR-2/InhA-IN-1 is a pyrazole-based dual inhibitor of InhA-VEGFR with anti-tuberculosis and anti-angiogenic activities. VEGFR-2/InhA-IN-1 has good antibacterial activity against Mycobacterium tuberculosis H37Rv strain (MIC=6.25 μg/mL) and significantly inhibits VEGFR-2 (IC50=15.27 nM)[1].
- Target Antigen: Bacterial; VEGFR
- Type: Reference compound
- Related Pathways: Anti-infection;Protein Tyrosine Kinase/RTK
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/vegfr-2-inha-in-1.html
- Smiles: O=C(NC1=CC=C(F)C=C1)NC2=CN(C3=CC=CC=C3)N=C2C4=CC=C(Cl)C=C4
- Molecular Weight: 406.84
- References & Citations: [1]Shaaban, et al. "The first-in-class pyrazole-based dual InhA-VEGFR inhibitors towards integrated antitubercular host-directed therapy." Bioorganic Chemistry 145 (2024): 107179.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported