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Lauric acid

CAT:
804-HY-Y0366-02
Size:
1 g
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Lauric acid - image 1

Lauric acid

  • CAS Number: 143-07-7
  • UNSPSC Description: Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively[1].
  • Target Antigen: Bacterial; Endogenous Metabolite
  • Type: Natural Products
  • Related Pathways: Anti-infection;Metabolic Enzyme/Protease
  • Applications: COVID-19-immunoregulation
  • Field of Research: Infection
  • Assay Protocol: https://www.medchemexpress.com/Lauric_acid.html
  • Purity: 99.98
  • Solubility: 0.1 M NaOH : 10 mg/mL (ultrasonic;warming;adjust pH to 11 with NaOH;heat to 60°C)|DMSO : 100 mg/mL (ultrasonic)
  • Smiles: CCCCCCCCCCCC(O)=O
  • Molecular Weight: 200.322
  • References & Citations: [1]Nakatsuji T, et al. Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. J Invest Dermatol. 2009 Oct;129(10):2480-8.|[2]Tham YY, et al. Lauric acid alleviates insulin resistance by improving mitochondrial biogenesis in THP-1 macrophages. Mol Biol Rep. 2020 Dec;47(12):9595-9607. |[3]Alves NF, et al. Acute Treatment with Lauric Acid Reduces Blood Pressure and Oxidative Stress in Spontaneously Hypertensive Rats. Basic Clin Pharmacol Toxicol. 2017 Apr;120(4):348-353.
  • Shipping Conditions: Room Temperature
  • Storage Conditions: 4°C (Powder, protect from light)
  • Clinical Information: Launched