Thiorphan

Thiorphan

• CAS Number: 76721-89-6
• UNSPSC Description: Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM[1].
• Target Antigen: Neprilysin
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/thiorphan.html
• Purity: 99.67
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: SCC(C(NCC(O)=O)=O)CC1=CC=CC=C1
• Molecular Weight: 253.323
• References & Citations: [1]Whyteside AR, Turner AJ. Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences. FEBS Lett. 2008 Jul 9;582(16):2382-6.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: No Development Reported