Desipramine (hydrochloride)
CAT:
804-HY-B1272-03
Size:
500 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Desipramine (hydrochloride)
- CAS Number: 58-28-6
- UNSPSC Description: Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively.
- Target Antigen: Dopamine Transporter; Serotonin Transporter
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Applications: Cancer-programmed cell death
- Field of Research: Neurological Disease; Cancer
- Assay Protocol: https://www.medchemexpress.com/desipramine-hydrochloride.html
- Purity: 99.92
- Solubility: DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)
- Smiles: CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31.[H]Cl
- Molecular Weight: 302.84
- References & Citations: [1]Torres GE, et al. Plasma membrane monoamine transporters: structure, regulation and function. Nat Rev Neurosci. 2003 Jan;4(1):13-25.|[2]Zhao Z, et al. Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. Neuropsychopharmacology. 2008 Dec;33(13):3190-200.Biochim Biophys Acta Mol Basis Dis. 2023 Mar 28;1869(5):166700.|Br J Pharmacol. 2024 Sep 5.|Glia. 2022 Jul 1.|Inflammation. 2021 Mar 4.|J Parkinson Dis. 2020;10(2):523-542.|Neural Regen Res. 2021;16:1660-70.|Neuroscience. 2024 Feb 8:542:11-20.|Neurotoxicology. 2022 Oct 6;S0161-813X(22)00156-5.|Parkinsons Dis-us. 2022.|Pharmaceutics. 2022, 14(8), 1523.|Sci Total Environ. 2024 Mar 1:923:171405.|Research Square Print. 2023 Feb 23.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched