LTV-1

LTV-1

• CAS Number: 347379-29-7
• UNSPSC Description: LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC50 of 508 nM. LTV-1 has the potential for autoimmunity treatment[1].
• Target Antigen: Phosphatase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/LTV-1.html
• Purity: 98.0
• Solubility: DMSO : 22.73 mg/mL (ultrasonic)
• Smiles: O=C(O)C1=CC=CC(COC2=CC=C(/C=C(C(N3C4=CC=CC=C4C)=O)\C(NC3=S)=O)C=C2)=C1
• Molecular Weight: 472.51
• References & Citations: [1]Vang T, et al. LYP inhibits T-cell activation when dissociated from CSK. Nat Chem Biol. 2012 Mar 18;8(5):437-446.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported