KRAS, Human (G12V, His)

KRAS, Human (G12V, His)

• UNSPSC Description: KRAS protein is a key Ras family member that binds GDP/GTP and has intrinsic GTPase activity. Its critical role in regulating cell proliferation emphasizes its importance in cellular processes. KRAS Protein, Human (G12V, His) is the recombinant human-derived KRAS protein, expressed by E. coli , with N-6*His labeled tag and G12V, , , , mutation. The total length of KRAS Protein, Human (G12V, His) is 184 a.a., with molecular weight of 25-30 kDa, observed by reducing SDS-PAGE.
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/kras-protein-human-g12v-his.html
• Purity: 95.00
• Smiles: HHHHHHTEYK LVVVGAVGVG KSALTIQLIQ NHFVDEYDPT IEDSYRKQVV IDGETCLLDI LDTAGHEEYS AMRDQYMRTG EGFLCVFAIN NTKSFEDIHH YREQIKRVKD SEDVPMVLVG NKCDLPSRTV DTKQAQDLAR SYGIPFIETS AKTRQGVDDA FYTLVREIRK HKEKMSKDGK KKKKKSKTKC
• Molecular Weight: 25-30 kDa, observed by reducing SDS-PAGE
• References & Citations: [1]Jianhua Ling, et al. KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. 2012 Jan 17;21(1):105-20.
• Shipping Conditions: Blue Ice
• Storage Conditions: Stored at -20°C for 2 years