Asfotase alfa
CAT:
804-HY-108786-03
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Asfotase alfa
- CAS Number: 1174277-80-5
- UNSPSC Description: Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2?/? knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP)[1].
- Target Antigen: Phosphatase
- Type: Inhibitory Antibodies
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/asfotase-alfa.html
- Purity: 97.88
- Solubility: 10 mM in DMSO
- Smiles: [Asfotase alfa]
- References & Citations: [1]Yadav MC, et al. Dose response of bone-targeted enzyme replacement for murine hypophosphatasia. Bone. 2011 Aug;49(2):250-6.
- Shipping Conditions: Dry Ice
- Storage Conditions: Store at -80°C for 2 years
- Clinical Information: Launched