TP-040
CAT:
804-HY-131979-05
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TP-040
- Product Name Alternative: O-GlcNAcase-IN-1
- CAS Number: 2757254-99-0
- UNSPSC Description: TP-040 (O-GlcNAcase-IN-1) is a potent and novel OGA inhibitor with an IC50 value of 46 nM.
- Target Antigen: OGA
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/tp-040.html
- Purity: 98.59
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: CC1CCN(C2=NC(NCC3=CN(C)C=N3)=NC=C2)CC1
- Molecular Weight: 286.38
- References & Citations: [1]Tawada M, et al. Discovery of a Novel and Brain-Penetrant O-GlcNAcase Inhibitor via Virtual Screening, Structure-Based Analysis, and Rational Lead Optimization. J Med Chem. 2021 Jan 28;64(2):1103-1115.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, stored under nitrogen)
- Clinical Information: No Development Reported