(S,R,S)-AHPC-PEG3-NH2 (hydrochloride)
CAT:
804-HY-103602-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
(S,R,S)-AHPC-PEG3-NH2 (hydrochloride)
- CAS Number: 2097971-11-2
- UNSPSC Description: (S,R,S)-AHPC-PEG3-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology.
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/E3_ligase_Ligand-Linker_Conjugates_5.html
- Purity: 99.01
- Solubility: DMSO : 200 mg/mL (ultrasonic)
- Smiles: O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCN)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
- Molecular Weight: 656.23
- References & Citations: [1]Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.
- Shipping Conditions: Dry Ice
- Storage Conditions: -80°C, protect from light, stored under nitrogen
- Clinical Information: No Development Reported