Cynomolgus LIV-1 / SLC39A6 Protein, His Tag, low endotoxin

Cynomolgus LIV-1 / SLC39A6 Protein, His Tag, low endotoxin

• Background: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.
• Description: Cynomolgus LIV-1, His Tag (LV1-C52H6) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Ile 309 (Accession # XP_005586923.1).
• Specifications: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.5 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression Region: Leu 21 - Ile 309
• Host: HEK 293
• Target: LIV-1
• Conjugation: Unconjugated
• Tag: C-10×His
• Source: Cynomolgus
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 0.05 EU per μg
• Purity: 90%
• Bioactivity: Immobilized Cynomolgus LIV-1, His Tag (Cat. No. LV1-C52H6) at 1 μg/mL (100 μL/well) can bind Anti-LIV-1 Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
• Format: Powder
• Buffer: PBS, pH7.4
• Additives: Trehalose
• Molecular Weight: 34.5 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C