(1R,3S-)Solifenacin-d5 (hydrochloride)
CAT:
804-HY-135329S-02
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(1R,3S-)Solifenacin-d5 (hydrochloride)
- CAS Number: 1217810-85-9
- UNSPSC Description: (1R,3S-)Solifenacin-d5 (hydrochloride) is the deuterium labeled Solifenacin D5 hydrochloride. Solifenacin D5 hydrochloride is a deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride is a muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, respectively[1].
- Target Antigen: Isotope-Labeled Compounds; mAChR
- Type: Isotope-Labeled Compounds
- Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
- Field of Research: Neurological Disease
- Smiles: O=C(N1[C@@H](C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C3=CC=CC=C3CC1)O[C@@H]4C5CCN(CC5)C4.Cl
- Molecular Weight: 403.96
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Ikeda K, et al. M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladderand salivary gland. Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):97-103.
- Shipping Conditions: Room temperature