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EGFR antibody

CAT:
710-FNab10146
Size:
100 µg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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EGFR antibody

  • Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
  • Synonyms: Epidermal growth factor receptor|Proto-oncogene c-ErbB-1|Receptor tyrosine-protein kinase erbB-1|EGFR|ERBB|ERBB1|HER1
  • CAS Number: 9007-83-4
  • Gene ID: 1956
  • UniProt: P00533
  • Host: Mouse
  • Reactivity: Human
  • Immunogen: epidermal growth factor receptor
  • Target: EGFR
  • Clonality: Monoclonal
  • Isotype: IgG1
  • Clone: 2C9
  • Applications: ELISA, WB, IHC
  • Field of Research: Signal Transduction, Immunology, Cancer
  • Purification: protein A+G purified
  • Dilution: WB: 1:2000 - 1:10000; IHC: 1:100 - 1:1000
  • Purity: ≥95% as determined by SDS-PAGE
  • Form: Liquid
  • Molecular Weight: 140-160 kDa
  • Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)