VTCN1 antibody

VTCN1 antibody

• Background: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells(Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
• Synonyms: V-set domain-containing T-cell activation inhibitor 1|B7 homolog 4 (B7-H4)|B7h.5|Immune costimulatory protein B7-H4|Protein B7S1|T-cell costimulatory molecule B7x|VTCN1|B7H4
• CAS Number: 9007-83-4
• Gene ID: 79679
• UniProt: Q7Z7D3
• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Immunogen: V-set domain containing T cell activation inhibitor 1
• Target: VTCN1
• Clonality: Polyclonal
• Isotype: IgG
• Applications: ELISA, IHC, WB
• Field of Research: Immunology, Cancer
• Purification: Immunogen affinity purified
• Dilution: WB: 1:200-1:2000; IHC: 1:50-1:200
• Purity: ≥95% as determined by SDS-PAGE
• Form: Liquid
• Molecular Weight: 50-80 kDa
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)