AP3B2 antibody

AP3B2 antibody

• Background: Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
• Synonyms: AP-3 complex subunit beta-2|Adaptor protein complex AP-3 subunit beta-2|Adaptor-related protein complex 3 subunit beta-2|Beta-3B-adaptin|Clathrin assembly protein complex 3 beta-2 large chain|Neuron-specific vesicle coat protein beta-NAP|AP3B2
• CAS Number: 9007-83-4
• Gene ID: 8120
• UniProt: Q13367
• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Immunogen: adaptor-related protein complex 3, beta 2 subunit
• Target: AP3B2
• Clonality: Polyclonal
• Isotype: IgG
• Applications: ELISA, WB,IP
• Field of Research: Signal Transduction, Metabolism
• Purification: Immunogen affinity purified
• Dilution: WB: 1:200-1:2000 IP: 1:200-1:2000
• Purity: ≥95% as determined by SDS-PAGE
• Form: Liquid
• Molecular Weight: 120-140 kDa
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)