Cusatuzumab
CAT:
804-HY-P99014-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
Cusatuzumab
- CAS Number: 1864871-20-4
- UNSPSC Description: Cusatuzumab is a human αCD70 monoclonal antibody. Cusatuzumab shows cytotoxicity activity with enhanced antibody-dependent cellular. Cusatuzumab reduces leukemia stem cells (LSCs) and triggers gene signatures related to myeloid differentiation and apoptosis. Cusatuzumab has the potential for the research of Acute myeloid leukemia (AML)[1].
- Target Antigen: Apoptosis
- Type: Inhibitory Antibodies
- Related Pathways: Apoptosis
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology; Cancer
- Assay Protocol: https://www.medchemexpress.com/cusatuzumab.html
- Purity: 98.80
- Solubility: H2O
- Smiles: [Cusatuzumab]
- References & Citations: [1]Riether C, et al. Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents. Nat Med. 2020; 26(9):1459-1467.
- Shipping Conditions: Dry Ice
- Storage Conditions: Store at -80°C for 2 years
- Clinical Information: Phase 2