Sar-[D-Phe8]-des-Arg9-Bradykinin

Sar-[D-Phe8]-des-Arg9-Bradykinin

• CAS Number: 126959-88-4
• UNSPSC Description: Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings[1].
• Target Antigen: Bradykinin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/sar-d-phe8-des-arg9-bradykinin.html
• Purity: 99.34
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C([C@H]1N(CCC1)C([C@H](CCCNC(N)=N)NC(CNC)=O)=O)N2[C@@H](CCC2)C(NCC(N[C@H](C(N[C@@H](CO)C(N3[C@@H](CCC3)C(N[C@@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=CC=C5)=O)=O
• Molecular Weight: 975.10
• References & Citations: [1]Levesque L, et al. Regulation of kinin-induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta. Br J Pharmacol. 1995 Sep;116(1):1673-9.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported