Enalapril

Enalapril

• CAS Number: 75847-73-3
• UNSPSC Description: Enalapril (MK-421) is an angiotensin-converting enzyme (ACE) inhibitor, can be used for hypertensive diseases research[1][2].
• Target Antigen: Angiotensin-converting Enzyme (ACE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/enalapril.html
• Purity: 97.80
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)[C@H]1N(C([C@H](C)N[C@H](C(OCC)=O)CCC2=CC=CC=C2)=O)CCC1
• Molecular Weight: 376.45
• References & Citations: [1]Serge Sicouri, et al. Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations. J Cardiovasc Electrophysiol. 2011 Jun;22(6):698-705.|[2]Rokhsareh Meamar, et al. Enalapril protects endothelial cells against induced apoptosis in Alzheimer's disease. J Res Med Sci. 2013 Mar;18(Suppl 1):S1-5.|[3]Talita A Cunha, et al. Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. AAPS PharmSciTech. 2013 Sep;14(3):1150-7.|[4]A Ravati, et al. Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats. Eur J Pharmacol. 1999 May 28;373(1):21-33.Am J Transl Res. 2022 Jan 15;14(1):211-222.|Int J Clin Exp Pathol. 2020 May 1;13(5):827-836.|Nat Commun. 2023 May 2;14(1):2523.|Ren Fail. 2023 Sep 19;45(2):2253924.|bioRxiv. 2024 November 28.|Environ Pollut. 2019 Apr;247:927-934.|Toxicol Lett. 2019 Jul;309:42-50.|Toxicology. 2023 Jan 24;153442.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Launched