Thymidine 5′-monophosphate p-nitrophenyl ester (sodium)

Thymidine 5′-monophosphate p-nitrophenyl ester (sodium)

• CAS Number: 98179-10-3
• UNSPSC Description: Thymidine 5′-monophosphate p-nitrophenyl ester sodium (Compound 2a) is the derivative of thymidine 5'-phosphate (TMP). Thymidine 5′-monophosphate p-nitrophenyl ester sodium penetrates mammalian cells, releases intracellular antimetabolite 5' nucleotides. Thymidine 5′-monophosphate p-nitrophenyl ester sodium is potential as an antitumor prodrug[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thymidine-5-monophosphate-p-nitrophenyl-ester-sodium.html
• Smiles: O=C(N1)N([C@@H]2O[C@H](COP(OC3=CC=C([N+]([O-])=O)C=C3)(O[Na])=O)[C@@H](O)C2)C=C(C)C1=O
• Molecular Weight: 465.28
• References & Citations: [1]Chawla RR, et al., Bis(m-nitrophenyl) and bis(p-nitrophenyl) esters and the phosphorodiamidate of thymidine 5'-phosphate as potential sources of intracellular thymidine 5'-phosphate in mouse cells in culture. J Med Chem. 1984 Dec;27(12):1733-6.
• Shipping Conditions: Room Temperature