AMPK-IN-3
CAT:
804-HY-151361-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AMPK-IN-3
- CAS Number: 2417674-27-0
- UNSPSC Description: AMPK-IN-3 (compound 67) is a potent and selective AMPK inhibitor with IC50s of 60.7, 107 and 3820 nM for AMPK (α2), AMPK (α1) and KDR, respectively. AMPK-IN-3 inhibits AMPK does not affect cell viability or cause significant cytotoxicity in K562 cells. AMPK-IN-3 can be used in study of cancer[1].
- Target Antigen: AMPK
- Type: Reference compound
- Related Pathways: Epigenetics;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ampk-in-3.html
- Solubility: DMSO : 115 mg/mL (ultrasonic)
- Smiles: O=C(/C(C1=C2)=C\C3=C(C(C(NCCN(CC)CC)=O)=C(N3)C)C)NC1=CC=C2CCC(N)=O
- Molecular Weight: 451.56
- References & Citations: [1]Matheson CJ, et al. Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitors. Eur J Med Chem. 2020 Jul 1;197:112316.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported