Zofenopril

Zofenopril

• CAS Number: 81872-10-8
• UNSPSC Description: Zofenopril is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 81 μM.
• Target Antigen: Angiotensin-converting Enzyme (ACE)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/Zofenopril.html
• Purity: 98.81
• Solubility: DMSO : 5 mg/mL (ultrasonic)
• Smiles: O=C(O)[C@H]1N(C([C@H](C)CSC(C2=CC=CC=C2)=O)=O)C[C@@H](SC3=CC=CC=C3)C1
• Molecular Weight: 429.55
• References & Citations: [1]Lin CJ, et al. Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter. Pharm Res. 1999 May;16(5):609-15.|[2]Sarro GD, et al. Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. Pharmacol Res. 2012 Mar;65(3):285-96.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched