Anti-PTBP2 Rabbit Monoclonal Antibody

Anti-PTBP2 Rabbit Monoclonal Antibody

• Description: Boster Bio Anti-PTBP2 Rabbit Monoclonal Antibody catalog # M05020. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
• Synonyms: Polypyrimidine tract-binding protein 2;Neural polypyrimidine tract-binding protein;Neurally-enriched homolog of PTB;PTB-like protein;PTBP2;NPTB, PTB, PTBLP;
• CAS Number: 9007-83-4
• Gene Name: Polypyrimidine tract-binding protein 2
• UniProt: Q9UKA9
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: A synthesized peptide derived from human PTBP2
• Clonality: Monoclonal
• Clone: Clone: ABF-16
• Tissue Specificity: Mainly expressed in brain although also detected in other tissues like heart and skeletal muscle. Isoform 1 and isoform 2 are specifically expressed in neuronal tissues. Isoform 3 and isoform 4 are expressed in non-neuronal tissues. Isoform 5 and isoform 6 are truncated forms expressed in non- neuronal tissues. .
• Applications: WB,IHC,ICC,IF
• Purification: Affinity-chromatography
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form: Liquid
• Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Function: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. .
• Components: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
• Storage Conditions: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 57491 MW
• Observed Molecular Weight: 54 kDa
• Fragment: Rabbit IgG
• Applications Notes: WB 1:500-1:2000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200
• Subcellular Location: Nucleus .
• Protein Name: T-cell surface glycoprotein CD3 zeta chain