Anti-Thyroglobulin TG Monoclonal Antibody

Anti-Thyroglobulin TG Monoclonal Antibody

• Background: Thyroglobulin (Tg) is synthesized by the follicular epithelial cells of the thyroid and secreted from the thyroid gland with the stimulation of TSH and/or thyroid stimulating immunoglobulins. Thyroglobulin is a prognostic marker for Graves` disease. Thyroglobulin antibody has been useful in the positive identification of thyroid carcinomas of the papillary and follicular types.
• Description: Boster Bio Anti-Thyroglobulin TG Monoclonal Antibody (Catalog # M00359). Tested in WB applications. This antibody reacts with Human, Mouse, Rat, Dog.
• Synonyms: Thyroglobulin, AITD 3, AITD3, hTG, TDH3, Tg, TGN
• CAS Number: 9007-83-4
• Gene Name: TG
• UniProt: P01266
• Host: Mouse
• Reactivity: Canine, Human, Mouse, Rat
• Cross Reactivity: No cross reactivity with other proteins.
• Immunogen: This protein A purified monoclonal antibody was produced by repeated immunizations with human thyroglobulin protein.
• Clonality: Monoclonal
• Applications: WB
• Purification: This protein A purified mouse monoclonal antibody reacts specifically with thyroglobulin in human tissues.  The antibody recognizes a 330-kDa band corresponding to thyroglobulin.  Cross-reactivity with thyroglobulin from mouse, rat and dog will occur.  Cross-reactivity with thyroglobulin from other sources has not been determined.
• Concentration: 1.6 mg/ml by UV absorbance at 280 nm
• Form: Liquid (sterile filtered)
• Molecular Weight: 304790 MW
• Components: 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide
• Storage Conditions: Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
• Fragment: IgG1
• Applications Notes: Anti-Thyroglobulin antibody has been tested by western blot and is suitable for the detection of thyroglobulin in ELISA, immunohistochemistry, and immunoprecipitation. For immunohistochemistry, both frozen sections and formalin fixed, paraffin-embedded tissue sections can be used without epitope retrieval or enzyme digestion. This antibody is specific for the 330 kDa thyroglobulin protein. Thyroglobulin shows a cytoplasmic localization. Thyroid tissue can be used as a positive control.
• Clone ID: Clone: Clone: 2H11