Cortistatin-14
CAT:
804-HY-P1932-04
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Cortistatin-14
- CAS Number: 186901-48-4
- UNSPSC Description: Cortistatin-14 is a neuropeptide that shares structural similarities with somatostatin, working by binding to somatostatin receptors (sst1-sst5). Cortistatin-14 (TFA) has anticonvulsant, neuroprotective effects, and significant anti-inflammatory properties[1][2][3].
- Target Antigen: Somatostatin Receptor
- Type: Peptides
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Inflammation/Immunology; Neurological Disease; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/cortistatin-14.html
- Purity: 99.21
- Solubility: H2O : 100 mg/mL (ultrasonic)
- Smiles: O=C(N[C@H]1CC2=CNC3=CC=CC=C23)[C@H](CC4=CC=CC=C4)NC([C@H](CC5=CC=CC=C5)NC([C@H](CC(N)=O)NC([C@H](CCCCN)NC([C@@H](NC([C@@H]6CCCN6)=O)CSSC[C@@H](C(N[C@@H](CCCCN)C(N)=O)=O)NC([C@H](CO)NC([C@H](CO)NC([C@H](CC7=CC=CC=C7)NC([C@]([H])([C@@H](C)O)NC([C@H](CCCCN)NC1=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
- Molecular Weight: 1720.03
- References & Citations: [1]Baranowska B, et al. Cortistatin and pituitary hormone secretion in rat. J Physiol Pharmacol. 2009 Mar;60(1):151-6.|[2]Braun H, et al. Protective effects of cortistatin (CST-14) against kainate-induced neurotoxicity in rat brain. Brain Res. 1998 Aug 24;803(1-2):54-60.|[3]Markovics A, et al. Comparison of the anti-inflammatory and anti-nociceptive effects of cortistatin-14 and somatostatin-14 in distinct in vitro and in vivo model systems. J Mol Neurosci. 2012 Jan;46(1):40-50.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported