Alloxan (hydrate)
CAT:
804-HY-W017227-01
Size:
1 g
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Alloxan (hydrate)
- CAS Number: 2244-11-3
- UNSPSC Description: Alloxan hydrate is a diabetogenic agent to induce diabetes. Alloxan hydrate is a proteasome inhibitor. Alloxan causes diabetes in experimental animals through its ability to destroy the insulin-secreting B-cells of the pancreas[1][2].
- Target Antigen: Proteasome
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/alloxan-hydrate.html
- Purity: 99.99
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
- Smiles: O=C(C(O)=N1)C(O)=NC1=O.O
- Molecular Weight: 160.08
- References & Citations: [1]Zhou W, et al. Diabetogenic agent alloxan is a proteasome inhibitor. Biochem Biophys Res Commun. 2017;488(2):400-406.|[2]Munday R, et al. The relationship between the physicochemical properties and the biological effects of alloxan and several N-alkyl substituted alloxan derivatives. J Endocrinol. 1993;139(1):153-163. |[3]Rerup C, et al. Streptozotocin-and alloxan-diabetes in mice[J]. European Journal of Pharmacology, 1969, 7(1): 89-96.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported