Propargyl-PEG3-NHS ester
CAT:
804-HY-126974-02
Size:
250 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Propargyl-PEG3-NHS ester
- CAS Number: 1428629-71-3
- UNSPSC Description: Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: ADC Linker; PROTAC Linkers
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/propargyl-peg2-c2-nhs-ester.html
- Purity: 97.0
- Solubility: DMSO : 200 mg/mL (ultrasonic)
- Smiles: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCC#C
- Molecular Weight: 313.30
- References & Citations: [1]Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, stored under nitrogen)
- Clinical Information: No Development Reported