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EGFR/HER2-IN-9

CAT:
804-HY-153111-02
Size:
10 mM / 1 mL
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
EGFR/HER2-IN-9 - image 1

EGFR/HER2-IN-9

  • CAS Number: 1637253-79-2
  • UNSPSC Description: EGFR/HER2-IN-9 (Compound 1) is an EGFR and HER2 inhibitor with IC50s of 3.2, 8.3 and 14 nM against EGFR, EGFR T790M and HER2, respectively[1].
  • Target Antigen: EGFR
  • Type: Reference compound
  • Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
  • Applications: Cancer-Kinase/protease
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/egfr-her2-in-9.html
  • Solubility: DMSO : 100 mg/mL (ultrasonic)
  • Smiles: COC(C(NC(/C=C/CN1C[C@@]2([H])[C@@](OCCO2)([H])C1)=O)=C3)=CC4=C3C(NC5=CC(Cl)=C(C=C5)F)=NC=N4
  • Molecular Weight: 513.95
  • References & Citations: [1]Yingjun Zhang, et al. Amino quinazoline derivatives as well as salts and application method thereof. Patent CN104119350A.
  • Shipping Conditions: Room Temperature
  • Clinical Information: No Development Reported