Doxazosin
CAT:
804-HY-B0098-03
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Doxazosin
- CAS Number: 74191-85-8
- UNSPSC Description: Doxazosin (UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.
- Target Antigen: Adrenergic Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cardiovascular Disease; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/doxazosin.html
- Purity: 99.85
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4OC5=CC=CC=C5OC4
- Molecular Weight: 451.48
- References & Citations: [1]Sun, J.A., et al., Stereoselective binding of doxazosin enantiomers to plasma proteins from rats, dogs and humans in vitro. Acta Pharmacol Sin, 2013. 34(12): p. 1568-74.|[2]D'Eletto, R.D. and N.B. Javitt, Effect of doxazosin on cholesterol synthesis in cell culture. J Cardiovasc Pharmacol, 1989. 13 Suppl 2: p. S1-4; discussion S4.|[3]Miura, Y. and K. Yoshinaga, Doxazosin: a newly developed, selective alpha 1-inhibitor in the management of patients with pheochromocytoma. Am Heart J, 1988. 116(6 Pt 2): p. 1785-9.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: Launched